| Zanesville to Southchase (Florida) | 800.69 mi (1,288.59 km) |
| Zanesville to Southern Pines (North Carolina) | 358.78 mi (577.39 km) |
| Zanesville to Southfield (Michigan) | 185.79 mi (298.99 km) |
| Zanesville to Southgate (Michigan) | 167.29 mi (269.22 km) |
| Zanesville to Southlake (Texas) | 968.46 mi (1,558.58 km) |
| Zanesville to Spanaway (Washington) | 2,059.10 mi (3,313.81 km) |
| Zanesville to Spanish Fork (Utah) | 1,560.07 mi (2,510.69 km) |
| Zanesville to Spanish Lake (Missouri) | 444.89 mi (715.98 km) |
| Zanesville to Spanish Springs (Nevada) | 1,983.73 mi (3,192.50 km) |
| Zanesville to Sparks (Nevada) | 1,987.44 mi (3,198.48 km) |
| Zanesville to Spartanburg (South Carolina) | 346.35 mi (557.40 km) |
| Zanesville to Spearfish (South Dakota) | 1,154.76 mi (1,858.41 km) |
| Zanesville to Speedway (Indiana) | 224.82 mi (361.81 km) |
| Zanesville to Spencer (Iowa) | 713.39 mi (1,148.09 km) |
| Zanesville to Spokane (Washington) | 1,826.64 mi (2,939.70 km) |
