| Zanesville to Enterprise (Nevada) | 1,818.60 mi (2,926.76 km) |
| Zanesville to Enumclaw (Washington) | 2,038.62 mi (3,280.85 km) |
| Zanesville to Ephrata (Pennsylvania) | 308.70 mi (496.81 km) |
| Zanesville to Erie (Colorado) | 1,215.39 mi (1,955.99 km) |
| Zanesville to Erie (Pennsylvania) | 180.26 mi (290.10 km) |
| Zanesville to Erlanger (Kentucky) | 151.97 mi (244.57 km) |
| Zanesville to Escanaba (Michigan) | 475.41 mi (765.10 km) |
| Zanesville to Escondido (California) | 1,988.65 mi (3,200.42 km) |
| Zanesville to Española (New Mexico) | 1,333.91 mi (2,146.71 km) |
| Zanesville to Essex (Maryland) | 299.69 mi (482.31 km) |
| Zanesville to Essex Junction (Vermont) | 552.16 mi (888.62 km) |
| Zanesville to Estelle (Louisiana) | 834.73 mi (1,343.36 km) |
| Zanesville to Estero (Florida) | 934.84 mi (1,504.48 km) |
| Zanesville to Euclid (Ohio) | 115.81 mi (186.38 km) |
| Zanesville to Eufaula (Alabama) | 582.88 mi (938.05 km) |
