| Ypsilanti to Southchase (Florida) | 966.08 mi (1,554.75 km) |
| Ypsilanti to Southern Pines (North Carolina) | 537.44 mi (864.92 km) |
| Ypsilanti to Southfield (Michigan) | 24.42 mi (39.30 km) |
| Ypsilanti to Southgate (Michigan) | 21.41 mi (34.46 km) |
| Ypsilanti to Southlake (Texas) | 977.86 mi (1,573.71 km) |
| Ypsilanti to Spanaway (Washington) | 1,915.56 mi (3,082.79 km) |
| Ypsilanti to Spanish Fork (Utah) | 1,457.99 mi (2,346.41 km) |
| Ypsilanti to Spanish Lake (Missouri) | 420.17 mi (676.19 km) |
| Ypsilanti to Spanish Springs (Nevada) | 1,875.59 mi (3,018.47 km) |
| Ypsilanti to Sparks (Nevada) | 1,879.68 mi (3,025.05 km) |
| Ypsilanti to Spartanburg (South Carolina) | 512.58 mi (824.92 km) |
| Ypsilanti to Spearfish (South Dakota) | 1,023.46 mi (1,647.10 km) |
| Ypsilanti to Speedway (Indiana) | 217.74 mi (350.42 km) |
| Ypsilanti to Spencer (Iowa) | 588.48 mi (947.07 km) |
| Ypsilanti to Spokane (Washington) | 1,680.88 mi (2,705.12 km) |
