| Wythenshawe to Southern Pines (North Carolina) | 3,812.06 mi (6,134.92 km) |
| Wythenshawe to Southfield (Michigan) | 3,616.68 mi (5,820.48 km) |
| Wythenshawe to Southgate (Michigan) | 3,627.16 mi (5,837.36 km) |
| Wythenshawe to Southlake (Texas) | 4,615.00 mi (7,427.12 km) |
| Wythenshawe to Spanaway (Washington) | 4,657.88 mi (7,496.14 km) |
| Wythenshawe to Spanish Fork (Utah) | 4,735.65 mi (7,621.30 km) |
| Wythenshawe to Spanish Lake (Missouri) | 4,055.64 mi (6,526.93 km) |
| Wythenshawe to Spanish Springs (Nevada) | 5,008.15 mi (8,059.83 km) |
| Wythenshawe to Sparks (Nevada) | 5,014.31 mi (8,069.75 km) |
| Wythenshawe to Spartanburg (South Carolina) | 3,924.71 mi (6,316.22 km) |
| Wythenshawe to Spearfish (South Dakota) | 4,248.30 mi (6,836.98 km) |
| Wythenshawe to Speedway (Indiana) | 3,856.80 mi (6,206.93 km) |
| Wythenshawe to Spencer (Iowa) | 4,020.87 mi (6,470.96 km) |
| Wythenshawe to Spokane (Washington) | 4,491.05 mi (7,227.64 km) |
| Wythenshawe to Spokane Valley (Washington) | 4,485.79 mi (7,219.18 km) |
