| Wylie to Orangeburg (South Carolina) | 903.77 mi (1,454.48 km) |
| Wylie to Orangevale (California) | 1,432.44 mi (2,305.29 km) |
| Wylie to Orchards (Washington) | 1,630.41 mi (2,623.88 km) |
| Wylie to Orcutt (California) | 1,372.71 mi (2,209.16 km) |
| Wylie to Oregon (Ohio) | 931.36 mi (1,498.88 km) |
| Wylie to Oregon (Wisconsin) | 785.09 mi (1,263.49 km) |
| Wylie to Oregon City (Oregon) | 1,623.83 mi (2,613.31 km) |
| Wylie to Orem (Utah) | 977.66 mi (1,573.39 km) |
| Wylie to Orinda (California) | 1,477.49 mi (2,377.80 km) |
| Wylie to Orland Park (Illinois) | 758.63 mi (1,220.90 km) |
| Wylie to Orlando (Florida) | 953.60 mi (1,534.67 km) |
| Wylie to Ormond Beach (Florida) | 946.17 mi (1,522.71 km) |
| Wylie to Oro Valley (Arizona) | 840.92 mi (1,353.33 km) |
| Wylie to Oroville (California) | 1,459.44 mi (2,348.74 km) |
| Wylie to Oshkosh (Wisconsin) | 871.38 mi (1,402.35 km) |
