| Wylie to Elyria (Ohio) | 978.07 mi (1,574.05 km) |
| Wylie to Emeryville (California) | 1,483.43 mi (2,387.35 km) |
| Wylie to Emmaus (Pennsylvania) | 1,269.06 mi (2,042.35 km) |
| Wylie to Emporia (Kansas) | 371.24 mi (597.45 km) |
| Wylie to Encinitas (California) | 1,199.54 mi (1,930.48 km) |
| Wylie to Endicott (New York) | 1,278.42 mi (2,057.41 km) |
| Wylie to Endwell (New York) | 1,280.95 mi (2,061.49 km) |
| Wylie to Englewood (Colorado) | 656.10 mi (1,055.89 km) |
| Wylie to Englewood (Florida) | 944.21 mi (1,519.55 km) |
| Wylie to Englewood (New Jersey) | 1,352.59 mi (2,176.79 km) |
| Wylie to Englewood (Ohio) | 825.19 mi (1,328.01 km) |
| Wylie to Enid (Oklahoma) | 245.21 mi (394.63 km) |
| Wylie to Ennis (Texas) | 49.59 mi (79.81 km) |
| Wylie to Ensley (Florida) | 569.66 mi (916.77 km) |
| Wylie to Enterprise (Alabama) | 634.72 mi (1,021.48 km) |
