| Wyandotte to Scottsbluff (Nebraska) | 1,049.97 mi (1,689.76 km) |
| Wyandotte to Scottsboro (Alabama) | 545.72 mi (878.25 km) |
| Wyandotte to Scottsdale (Arizona) | 1,661.68 mi (2,674.22 km) |
| Wyandotte to Scranton (Pennsylvania) | 389.67 mi (627.11 km) |
| Wyandotte to Seabrook (Maryland) | 398.92 mi (642.00 km) |
| Wyandotte to Seabrook (Texas) | 1,094.70 mi (1,761.75 km) |
| Wyandotte to Seaford (New York) | 511.47 mi (823.13 km) |
| Wyandotte to Seagoville (Texas) | 985.63 mi (1,586.22 km) |
| Wyandotte to Seal Beach (California) | 1,973.64 mi (3,176.26 km) |
| Wyandotte to Searcy (Arkansas) | 666.94 mi (1,073.34 km) |
| Wyandotte to Seaside (California) | 2,081.25 mi (3,349.45 km) |
| Wyandotte to SeaTac (Washington) | 1,930.69 mi (3,107.14 km) |
| Wyandotte to Seattle (Washington) | 1,931.11 mi (3,107.82 km) |
| Wyandotte to Sebastian (Florida) | 1,008.23 mi (1,622.58 km) |
| Wyandotte to Sebring (Florida) | 1,022.55 mi (1,645.63 km) |
