| Wyandotte to Oskaloosa (Iowa) | 492.74 mi (792.99 km) |
| Wyandotte to Oswego (Illinois) | 268.71 mi (432.45 km) |
| Wyandotte to Oswego (New York) | 347.83 mi (559.79 km) |
| Wyandotte to Otsego (Minnesota) | 562.87 mi (905.85 km) |
| Wyandotte to Ottawa (Illinois) | 298.00 mi (479.59 km) |
| Wyandotte to Ottawa (Kansas) | 683.38 mi (1,099.80 km) |
| Wyandotte to Ottumwa (Iowa) | 485.25 mi (780.94 km) |
| Wyandotte to Overland (Missouri) | 450.07 mi (724.32 km) |
| Wyandotte to Overland Park (Kansas) | 646.84 mi (1,040.99 km) |
| Wyandotte to Overlea (Maryland) | 398.94 mi (642.04 km) |
| Wyandotte to Oviedo (Florida) | 942.90 mi (1,517.45 km) |
| Wyandotte to Owasso (Oklahoma) | 790.87 mi (1,272.78 km) |
| Wyandotte to Owatonna (Minnesota) | 523.84 mi (843.04 km) |
| Wyandotte to Owensboro (Kentucky) | 372.29 mi (599.15 km) |
| Wyandotte to Owings Mills (Maryland) | 384.81 mi (619.29 km) |
