| Worthington to Sunset (Florida) | 1,006.02 mi (1,619.03 km) |
| Worthington to Superior (Colorado) | 1,168.49 mi (1,880.51 km) |
| Worthington to Superior (Wisconsin) | 643.28 mi (1,035.27 km) |
| Worthington to Surprise (Arizona) | 1,677.13 mi (2,699.08 km) |
| Worthington to Susanville (California) | 1,967.10 mi (3,165.74 km) |
| Worthington to Sussex (Wisconsin) | 340.92 mi (548.66 km) |
| Worthington to Suwanee (Georgia) | 421.58 mi (678.47 km) |
| Worthington to Swansea (Illinois) | 387.14 mi (623.04 km) |
| Worthington to Sweetwater (Florida) | 1,000.85 mi (1,610.72 km) |
| Worthington to Sweetwater (Texas) | 1,099.73 mi (1,769.84 km) |
| Worthington to Sycamore (Illinois) | 322.83 mi (519.54 km) |
| Worthington to Sylacauga (Alabama) | 510.45 mi (821.49 km) |
| Worthington to Sylvania (Ohio) | 117.23 mi (188.67 km) |
| Worthington to Syosset (New York) | 502.67 mi (808.96 km) |
| Worthington to Syracuse (New York) | 409.45 mi (658.94 km) |
