| Worthington to Stony Brook (New York) | 522.50 mi (840.88 km) |
| Worthington to Storm Lake (Iowa) | 654.73 mi (1,053.68 km) |
| Worthington to Storrs (Connecticut) | 573.91 mi (923.62 km) |
| Worthington to Stoughton (Wisconsin) | 375.56 mi (604.40 km) |
| Worthington to Stow (Ohio) | 111.81 mi (179.95 km) |
| Worthington to Streamwood (Illinois) | 299.75 mi (482.40 km) |
| Worthington to Streator (Illinois) | 312.81 mi (503.43 km) |
| Worthington to Streetsboro (Ohio) | 118.16 mi (190.16 km) |
| Worthington to Strongsville (Ohio) | 104.70 mi (168.50 km) |
| Worthington to Stuart (Florida) | 905.30 mi (1,456.93 km) |
| Worthington to Stuarts Draft (Virginia) | 257.45 mi (414.32 km) |
| Worthington to Sturgis (Michigan) | 171.79 mi (276.48 km) |
| Worthington to Suamico (Wisconsin) | 405.79 mi (653.06 km) |
| Worthington to Sudley (Virginia) | 308.26 mi (496.10 km) |
| Worthington to Suffern (New York) | 470.83 mi (757.72 km) |
