| Worthington to Southchase (Florida) | 814.77 mi (1,311.25 km) |
| Worthington to Southern Pines (North Carolina) | 392.19 mi (631.17 km) |
| Worthington to Southfield (Michigan) | 165.02 mi (265.57 km) |
| Worthington to Southgate (Michigan) | 146.08 mi (235.10 km) |
| Worthington to Southlake (Texas) | 925.01 mi (1,488.66 km) |
| Worthington to Spanaway (Washington) | 2,007.33 mi (3,230.48 km) |
| Worthington to Spanish Fork (Utah) | 1,505.90 mi (2,423.52 km) |
| Worthington to Spanish Lake (Missouri) | 393.84 mi (633.82 km) |
| Worthington to Spanish Springs (Nevada) | 1,929.57 mi (3,105.35 km) |
| Worthington to Sparks (Nevada) | 1,933.28 mi (3,111.32 km) |
| Worthington to Spartanburg (South Carolina) | 360.91 mi (580.82 km) |
| Worthington to Spearfish (South Dakota) | 1,101.91 mi (1,773.36 km) |
| Worthington to Speedway (Indiana) | 172.20 mi (277.13 km) |
| Worthington to Spencer (Iowa) | 660.45 mi (1,062.90 km) |
| Worthington to Spokane (Washington) | 1,775.28 mi (2,857.03 km) |
