| Worthington to Oskaloosa (Iowa) | 510.40 mi (821.41 km) |
| Worthington to Oswego (Illinois) | 298.52 mi (480.42 km) |
| Worthington to Oswego (New York) | 408.06 mi (656.71 km) |
| Worthington to Otsego (Minnesota) | 645.30 mi (1,038.51 km) |
| Worthington to Ottawa (Illinois) | 316.13 mi (508.76 km) |
| Worthington to Ottawa (Kansas) | 661.70 mi (1,064.90 km) |
| Worthington to Ottumwa (Iowa) | 497.19 mi (800.15 km) |
| Worthington to Overland (Missouri) | 403.93 mi (650.06 km) |
| Worthington to Overland Park (Kansas) | 627.16 mi (1,009.31 km) |
| Worthington to Overlea (Maryland) | 349.16 mi (561.92 km) |
| Worthington to Oviedo (Florida) | 797.05 mi (1,282.73 km) |
| Worthington to Owasso (Oklahoma) | 742.86 mi (1,195.51 km) |
| Worthington to Owatonna (Minnesota) | 591.25 mi (951.52 km) |
| Worthington to Owensboro (Kentucky) | 273.01 mi (439.37 km) |
| Worthington to Owings Mills (Maryland) | 334.19 mi (537.83 km) |
