| Winter Springs to Scottsbluff (Nebraska) | 1,549.13 mi (2,493.09 km) |
| Winter Springs to Scottsboro (Alabama) | 498.09 mi (801.60 km) |
| Winter Springs to Scottsdale (Arizona) | 1,834.09 mi (2,951.69 km) |
| Winter Springs to Scranton (Pennsylvania) | 933.46 mi (1,502.26 km) |
| Winter Springs to Seabrook (Maryland) | 754.68 mi (1,214.54 km) |
| Winter Springs to Seabrook (Texas) | 831.81 mi (1,338.67 km) |
| Winter Springs to Seaford (New York) | 937.29 mi (1,508.42 km) |
| Winter Springs to Seagoville (Texas) | 947.17 mi (1,524.32 km) |
| Winter Springs to Seal Beach (California) | 2,190.74 mi (3,525.65 km) |
| Winter Springs to Searcy (Arkansas) | 761.63 mi (1,225.73 km) |
| Winter Springs to Seaside (California) | 2,403.09 mi (3,867.40 km) |
| Winter Springs to SeaTac (Washington) | 2,539.66 mi (4,087.19 km) |
| Winter Springs to Seattle (Washington) | 2,544.16 mi (4,094.43 km) |
| Winter Springs to Sebastian (Florida) | 78.92 mi (127.00 km) |
| Winter Springs to Sebring (Florida) | 84.47 mi (135.94 km) |
