| Winter Springs to Enterprise (Nevada) | 2,034.47 mi (3,274.17 km) |
| Winter Springs to Enumclaw (Washington) | 2,521.18 mi (4,057.45 km) |
| Winter Springs to Ephrata (Pennsylvania) | 844.92 mi (1,359.77 km) |
| Winter Springs to Erie (Colorado) | 1,558.85 mi (2,508.72 km) |
| Winter Springs to Erie (Pennsylvania) | 930.19 mi (1,496.99 km) |
| Winter Springs to Erlanger (Kentucky) | 737.97 mi (1,187.65 km) |
| Winter Springs to Escanaba (Michigan) | 1,220.51 mi (1,964.21 km) |
| Winter Springs to Escondido (California) | 2,134.05 mi (3,434.43 km) |
| Winter Springs to Española (New Mexico) | 1,528.08 mi (2,459.21 km) |
| Winter Springs to Essex (Maryland) | 783.33 mi (1,260.65 km) |
| Winter Springs to Essex Junction (Vermont) | 1,180.30 mi (1,899.51 km) |
| Winter Springs to Estelle (Louisiana) | 538.14 mi (866.05 km) |
| Winter Springs to Estero (Florida) | 159.51 mi (256.71 km) |
| Winter Springs to Euclid (Ohio) | 891.51 mi (1,434.75 km) |
| Winter Springs to Eufaula (Alabama) | 321.07 mi (516.71 km) |
