| Winter Park to Enterprise (Nevada) | 2,032.81 mi (3,271.50 km) |
| Winter Park to Enumclaw (Washington) | 2,521.99 mi (4,058.76 km) |
| Winter Park to Ephrata (Pennsylvania) | 852.25 mi (1,371.57 km) |
| Winter Park to Erie (Colorado) | 1,558.96 mi (2,508.90 km) |
| Winter Park to Erie (Pennsylvania) | 936.70 mi (1,507.47 km) |
| Winter Park to Erlanger (Kentucky) | 742.94 mi (1,195.64 km) |
| Winter Park to Escanaba (Michigan) | 1,225.52 mi (1,972.28 km) |
| Winter Park to Escondido (California) | 2,131.64 mi (3,430.55 km) |
| Winter Park to Española (New Mexico) | 1,526.75 mi (2,457.07 km) |
| Winter Park to Essex (Maryland) | 790.68 mi (1,272.48 km) |
| Winter Park to Essex Junction (Vermont) | 1,187.68 mi (1,911.39 km) |
| Winter Park to Estelle (Louisiana) | 534.93 mi (860.89 km) |
| Winter Park to Estero (Florida) | 152.55 mi (245.50 km) |
| Winter Park to Euclid (Ohio) | 897.67 mi (1,444.66 km) |
| Winter Park to Eufaula (Alabama) | 322.36 mi (518.79 km) |
