| Winter Garden to Enterprise (Nevada) | 2,020.31 mi (3,251.38 km) |
| Winter Garden to Enumclaw (Washington) | 2,513.23 mi (4,044.66 km) |
| Winter Garden to Ephrata (Pennsylvania) | 860.98 mi (1,385.62 km) |
| Winter Garden to Erie (Colorado) | 1,549.05 mi (2,492.95 km) |
| Winter Garden to Erie (Pennsylvania) | 941.79 mi (1,515.67 km) |
| Winter Garden to Erlanger (Kentucky) | 743.29 mi (1,196.21 km) |
| Winter Garden to Escanaba (Michigan) | 1,225.91 mi (1,972.91 km) |
| Winter Garden to Escondido (California) | 2,118.22 mi (3,408.95 km) |
| Winter Garden to Española (New Mexico) | 1,514.71 mi (2,437.69 km) |
| Winter Garden to Essex (Maryland) | 799.58 mi (1,286.80 km) |
| Winter Garden to Essex Junction (Vermont) | 1,196.71 mi (1,925.92 km) |
| Winter Garden to Estelle (Louisiana) | 520.72 mi (838.02 km) |
| Winter Garden to Estero (Florida) | 146.60 mi (235.93 km) |
| Winter Garden to Euclid (Ohio) | 901.55 mi (1,450.91 km) |
| Winter Garden to Eufaula (Alabama) | 314.86 mi (506.72 km) |
