| Wilmington to St. Petersburg (Florida) | 525.81 mi (846.20 km) |
| Wilmington to St. Simons (Georgia) | 292.01 mi (469.94 km) |
| Wilmington to Stafford (Texas) | 1,082.39 mi (1,741.94 km) |
| Wilmington to Stallings (North Carolina) | 169.40 mi (272.62 km) |
| Wilmington to Stamford (Connecticut) | 531.73 mi (855.74 km) |
| Wilmington to Stanford (California) | 2,468.14 mi (3,972.08 km) |
| Wilmington to Stanton (California) | 2,282.24 mi (3,672.91 km) |
| Wilmington to Star (Idaho) | 2,153.48 mi (3,465.69 km) |
| Wilmington to Starkville (Mississippi) | 629.87 mi (1,013.67 km) |
| Wilmington to State College (Pennsylvania) | 454.71 mi (731.78 km) |
| Wilmington to Staten Island (New York) | 485.67 mi (781.61 km) |
| Wilmington to Statesboro (Georgia) | 255.69 mi (411.50 km) |
| Wilmington to Statesville (North Carolina) | 200.91 mi (323.33 km) |
| Wilmington to Staunton (Virginia) | 280.62 mi (451.61 km) |
| Wilmington to Steamboat Springs (Colorado) | 1,639.28 mi (2,638.16 km) |
