| Wilmington to Smithville (Missouri) | 988.37 mi (1,590.63 km) |
| Wilmington to Smyrna (Delaware) | 373.16 mi (600.55 km) |
| Wilmington to Smyrna (Georgia) | 380.31 mi (612.05 km) |
| Wilmington to Smyrna (Tennessee) | 503.16 mi (809.75 km) |
| Wilmington to Snellville (Georgia) | 351.06 mi (564.98 km) |
| Wilmington to Snoqualmie (Washington) | 2,435.20 mi (3,919.08 km) |
| Wilmington to Snyder (Texas) | 1,328.39 mi (2,137.84 km) |
| Wilmington to Socastee (South Carolina) | 73.76 mi (118.70 km) |
| Wilmington to Socorro (Texas) | 1,649.79 mi (2,655.08 km) |
| Wilmington to Soddy-Daisy (Tennessee) | 419.96 mi (675.86 km) |
| Wilmington to Solana Beach (California) | 2,253.09 mi (3,625.99 km) |
| Wilmington to Soledad (California) | 2,433.81 mi (3,916.84 km) |
| Wilmington to Solon (Ohio) | 532.32 mi (856.69 km) |
| Wilmington to Somers Point (New Jersey) | 396.74 mi (638.49 km) |
| Wilmington to Somerset (Kentucky) | 426.42 mi (686.25 km) |
