| Wilmington to Siloam Springs (Arkansas) | 948.43 mi (1,526.36 km) |
| Wilmington to Silver Firs (Washington) | 2,451.90 mi (3,945.94 km) |
| Wilmington to Silver Spring (Maryland) | 334.62 mi (538.51 km) |
| Wilmington to Silver Springs Shores (Florida) | 427.66 mi (688.25 km) |
| Wilmington to Silverdale (Washington) | 2,475.16 mi (3,983.38 km) |
| Wilmington to Silverton (Oregon) | 2,468.50 mi (3,972.67 km) |
| Wilmington to Simi Valley (California) | 2,317.87 mi (3,730.26 km) |
| Wilmington to Simpsonville (South Carolina) | 251.49 mi (404.73 km) |
| Wilmington to Sioux City (Iowa) | 1,150.87 mi (1,852.14 km) |
| Wilmington to Sioux Falls (South Dakota) | 1,196.94 mi (1,926.28 km) |
| Wilmington to Skokie (Illinois) | 760.06 mi (1,223.20 km) |
| Wilmington to Sleepy Hollow (New York) | 523.71 mi (842.82 km) |
| Wilmington to Slidell (Louisiana) | 745.47 mi (1,199.72 km) |
| Wilmington to Smithfield (North Carolina) | 93.80 mi (150.96 km) |
| Wilmington to Smithfield (Utah) | 1,907.19 mi (3,069.32 km) |
