| Wilmington to Secaucus (New Jersey) | 499.86 mi (804.45 km) |
| Wilmington to Security-Widefield (Colorado) | 1,517.28 mi (2,441.83 km) |
| Wilmington to Sedalia (Missouri) | 906.29 mi (1,458.54 km) |
| Wilmington to Sedro-Woolley (Washington) | 2,460.77 mi (3,960.22 km) |
| Wilmington to Seguin (Texas) | 1,218.12 mi (1,960.37 km) |
| Wilmington to Selden (New York) | 530.96 mi (854.50 km) |
| Wilmington to Selma (Alabama) | 542.27 mi (872.70 km) |
| Wilmington to Selma (California) | 2,337.64 mi (3,762.06 km) |
| Wilmington to Selma (Texas) | 1,237.65 mi (1,991.81 km) |
| Wilmington to Seminole (Florida) | 526.67 mi (847.59 km) |
| Wilmington to Seven Hills (Ohio) | 536.69 mi (863.72 km) |
| Wilmington to Seven Oaks (South Carolina) | 186.60 mi (300.31 km) |
| Wilmington to Severn (Maryland) | 346.66 mi (557.89 km) |
| Wilmington to Severna Park (Maryland) | 344.79 mi (554.89 km) |
| Wilmington to Sevierville (Tennessee) | 341.54 mi (549.66 km) |
