| Wilmington to Orangeburg (South Carolina) | 178.05 mi (286.54 km) |
| Wilmington to Orangevale (California) | 2,405.78 mi (3,871.73 km) |
| Wilmington to Orchards (Washington) | 2,458.19 mi (3,956.08 km) |
| Wilmington to Orcutt (California) | 2,402.78 mi (3,866.90 km) |
| Wilmington to Oregon (Ohio) | 596.13 mi (959.38 km) |
| Wilmington to Oregon (Wisconsin) | 863.76 mi (1,390.08 km) |
| Wilmington to Oregon City (Oregon) | 2,460.13 mi (3,959.19 km) |
| Wilmington to Orem (Utah) | 1,894.34 mi (3,048.64 km) |
| Wilmington to Orinda (California) | 2,464.26 mi (3,965.84 km) |
| Wilmington to Orland Park (Illinois) | 745.33 mi (1,199.49 km) |
| Wilmington to Orlando (Florida) | 445.27 mi (716.59 km) |
| Wilmington to Ormond Beach (Florida) | 388.30 mi (624.91 km) |
| Wilmington to Oro Valley (Arizona) | 1,906.22 mi (3,067.76 km) |
| Wilmington to Oroville (California) | 2,418.36 mi (3,891.97 km) |
| Wilmington to Oshkosh (Wisconsin) | 885.67 mi (1,425.35 km) |
