| Wilmington to Enterprise (Nevada) | 2,101.37 mi (3,381.83 km) |
| Wilmington to Enumclaw (Washington) | 2,439.90 mi (3,926.64 km) |
| Wilmington to Ephrata (Pennsylvania) | 423.09 mi (680.89 km) |
| Wilmington to Erie (Colorado) | 1,542.46 mi (2,482.35 km) |
| Wilmington to Erie (Pennsylvania) | 559.02 mi (899.65 km) |
| Wilmington to Erlanger (Kentucky) | 497.83 mi (801.19 km) |
| Wilmington to Escanaba (Michigan) | 932.86 mi (1,501.29 km) |
| Wilmington to Escondido (California) | 2,240.45 mi (3,605.65 km) |
| Wilmington to Española (New Mexico) | 1,592.23 mi (2,562.45 km) |
| Wilmington to Essex (Maryland) | 360.76 mi (580.59 km) |
| Wilmington to Essex Junction (Vermont) | 754.32 mi (1,213.97 km) |
| Wilmington to Estelle (Louisiana) | 775.81 mi (1,248.55 km) |
| Wilmington to Estero (Florida) | 585.91 mi (942.94 km) |
| Wilmington to Euclid (Ohio) | 546.89 mi (880.14 km) |
| Wilmington to Eufaula (Alabama) | 449.50 mi (723.41 km) |
