| Wilmington to Elyria (Ohio) | 545.92 mi (878.57 km) |
| Wilmington to Emeryville (California) | 2,470.84 mi (3,976.43 km) |
| Wilmington to Emmaus (Pennsylvania) | 456.24 mi (734.25 km) |
| Wilmington to Emporia (Kansas) | 1,057.63 mi (1,702.09 km) |
| Wilmington to Encinitas (California) | 2,252.42 mi (3,624.93 km) |
| Wilmington to Endicott (New York) | 553.90 mi (891.41 km) |
| Wilmington to Endwell (New York) | 555.69 mi (894.30 km) |
| Wilmington to Englewood (Colorado) | 1,537.19 mi (2,473.87 km) |
| Wilmington to Englewood (Florida) | 566.09 mi (911.04 km) |
| Wilmington to Englewood (New Jersey) | 508.85 mi (818.92 km) |
| Wilmington to Englewood (Ohio) | 526.97 mi (848.08 km) |
| Wilmington to Enid (Oklahoma) | 1,134.84 mi (1,826.35 km) |
| Wilmington to Ennis (Texas) | 1,089.31 mi (1,753.08 km) |
| Wilmington to Ensley (Florida) | 603.69 mi (971.55 km) |
| Wilmington to Enterprise (Alabama) | 503.30 mi (809.99 km) |
