| Willoughby to Sunset (Florida) | 1,102.99 mi (1,775.08 km) |
| Willoughby to Superior (Colorado) | 1,244.07 mi (2,002.13 km) |
| Willoughby to Superior (Wisconsin) | 632.77 mi (1,018.35 km) |
| Willoughby to Surprise (Arizona) | 1,773.69 mi (2,854.49 km) |
| Willoughby to Susanville (California) | 2,027.36 mi (3,262.72 km) |
| Willoughby to Sussex (Wisconsin) | 362.50 mi (583.39 km) |
| Willoughby to Suwanee (Georgia) | 544.39 mi (876.11 km) |
| Willoughby to Swansea (Illinois) | 500.93 mi (806.17 km) |
| Willoughby to Sweetwater (Florida) | 1,097.91 mi (1,766.92 km) |
| Willoughby to Sweetwater (Texas) | 1,220.49 mi (1,964.19 km) |
| Willoughby to Sycamore (Illinois) | 375.19 mi (603.81 km) |
| Willoughby to Sylacauga (Alabama) | 642.53 mi (1,034.06 km) |
| Willoughby to Sylvania (Ohio) | 118.81 mi (191.21 km) |
| Willoughby to Syosset (New York) | 414.67 mi (667.34 km) |
| Willoughby to Syracuse (New York) | 285.55 mi (459.54 km) |
