| Willoughby to Stony Brook (New York) | 432.84 mi (696.59 km) |
| Willoughby to Storm Lake (Iowa) | 708.89 mi (1,140.85 km) |
| Willoughby to Storrs (Connecticut) | 472.10 mi (759.77 km) |
| Willoughby to Stoughton (Wisconsin) | 408.90 mi (658.06 km) |
| Willoughby to Stow (Ohio) | 32.46 mi (52.24 km) |
| Willoughby to Streamwood (Illinois) | 349.37 mi (562.25 km) |
| Willoughby to Streator (Illinois) | 386.28 mi (621.65 km) |
| Willoughby to Streetsboro (Ohio) | 28.26 mi (45.48 km) |
| Willoughby to Strongsville (Ohio) | 31.76 mi (51.12 km) |
| Willoughby to Stuart (Florida) | 1,000.57 mi (1,610.26 km) |
| Willoughby to Stuarts Draft (Virginia) | 280.43 mi (451.31 km) |
| Willoughby to Sturgis (Michigan) | 207.05 mi (333.21 km) |
| Willoughby to Suamico (Wisconsin) | 394.02 mi (634.11 km) |
| Willoughby to Sudley (Virginia) | 285.60 mi (459.63 km) |
| Willoughby to Suffern (New York) | 378.38 mi (608.95 km) |
