| Willoughby to Southchase (Florida) | 916.63 mi (1,475.18 km) |
| Willoughby to Southern Pines (North Carolina) | 458.85 mi (738.44 km) |
| Willoughby to Southfield (Michigan) | 110.99 mi (178.62 km) |
| Willoughby to Southgate (Michigan) | 100.13 mi (161.15 km) |
| Willoughby to Southlake (Texas) | 1,050.48 mi (1,690.59 km) |
| Willoughby to Spanaway (Washington) | 2,036.21 mi (3,276.96 km) |
| Willoughby to Spanish Fork (Utah) | 1,574.84 mi (2,534.46 km) |
| Willoughby to Spanish Lake (Missouri) | 504.17 mi (811.39 km) |
| Willoughby to Spanish Springs (Nevada) | 1,993.88 mi (3,208.84 km) |
| Willoughby to Sparks (Nevada) | 1,997.90 mi (3,215.31 km) |
| Willoughby to Spartanburg (South Carolina) | 463.89 mi (746.55 km) |
| Willoughby to Spearfish (South Dakota) | 1,144.21 mi (1,841.43 km) |
| Willoughby to Speedway (Indiana) | 283.86 mi (456.82 km) |
| Willoughby to Spencer (Iowa) | 708.14 mi (1,139.64 km) |
| Willoughby to Spokane (Washington) | 1,801.36 mi (2,899.02 km) |
