| Willoughby to Enterprise (Nevada) | 1,849.08 mi (2,975.81 km) |
| Willoughby to Enumclaw (Washington) | 2,015.34 mi (3,243.38 km) |
| Willoughby to Ephrata (Pennsylvania) | 291.03 mi (468.37 km) |
| Willoughby to Erie (Colorado) | 1,236.28 mi (1,989.60 km) |
| Willoughby to Erie (Pennsylvania) | 75.99 mi (122.30 km) |
| Willoughby to Erlanger (Kentucky) | 247.28 mi (397.96 km) |
| Willoughby to Escanaba (Michigan) | 400.89 mi (645.17 km) |
| Willoughby to Escondido (California) | 2,028.00 mi (3,263.75 km) |
| Willoughby to Española (New Mexico) | 1,378.03 mi (2,217.73 km) |
| Willoughby to Essex (Maryland) | 306.98 mi (494.03 km) |
| Willoughby to Essex Junction (Vermont) | 462.19 mi (743.83 km) |
| Willoughby to Estelle (Louisiana) | 948.80 mi (1,526.95 km) |
| Willoughby to Estero (Florida) | 1,051.71 mi (1,692.57 km) |
| Willoughby to Euclid (Ohio) | 6.88 mi (11.07 km) |
| Willoughby to Eufaula (Alabama) | 703.63 mi (1,132.38 km) |
