| Williamsport to Southchase (Florida) | 921.91 mi (1,483.68 km) |
| Williamsport to Southern Pines (North Carolina) | 437.08 mi (703.41 km) |
| Williamsport to Southfield (Michigan) | 331.38 mi (533.30 km) |
| Williamsport to Southgate (Michigan) | 324.95 mi (522.95 km) |
| Williamsport to Southlake (Texas) | 1,243.35 mi (2,000.97 km) |
| Williamsport to Spanaway (Washington) | 2,252.83 mi (3,625.58 km) |
| Williamsport to Spanish Fork (Utah) | 1,802.94 mi (2,901.56 km) |
| Williamsport to Spanish Lake (Missouri) | 716.47 mi (1,153.05 km) |
| Williamsport to Spanish Springs (Nevada) | 2,221.64 mi (3,575.38 km) |
| Williamsport to Sparks (Nevada) | 2,225.69 mi (3,581.91 km) |
| Williamsport to Spartanburg (South Carolina) | 509.56 mi (820.06 km) |
| Williamsport to Spearfish (South Dakota) | 1,368.26 mi (2,202.00 km) |
| Williamsport to Speedway (Indiana) | 493.78 mi (794.65 km) |
| Williamsport to Spencer (Iowa) | 934.81 mi (1,504.43 km) |
| Williamsport to Spokane (Washington) | 2,017.04 mi (3,246.11 km) |
