| Williamsport to Scottsbluff (Nebraska) | 1,371.77 mi (2,207.65 km) |
| Williamsport to Scottsboro (Alabama) | 669.26 mi (1,077.07 km) |
| Williamsport to Scottsdale (Arizona) | 1,965.61 mi (3,163.34 km) |
| Williamsport to Scranton (Pennsylvania) | 72.10 mi (116.03 km) |
| Williamsport to Seabrook (Maryland) | 156.44 mi (251.77 km) |
| Williamsport to Seabrook (Texas) | 1,289.87 mi (2,075.84 km) |
| Williamsport to Seaford (New York) | 189.14 mi (304.38 km) |
| Williamsport to Seagoville (Texas) | 1,225.77 mi (1,972.69 km) |
| Williamsport to Seal Beach (California) | 2,285.85 mi (3,678.72 km) |
| Williamsport to Searcy (Arkansas) | 897.19 mi (1,443.88 km) |
| Williamsport to Seaside (California) | 2,401.28 mi (3,864.49 km) |
| Williamsport to SeaTac (Washington) | 2,244.40 mi (3,612.01 km) |
| Williamsport to Seattle (Washington) | 2,244.35 mi (3,611.93 km) |
| Williamsport to Sebastian (Florida) | 950.07 mi (1,528.99 km) |
| Williamsport to Sebring (Florida) | 983.34 mi (1,582.53 km) |
