| West Mifflin to Southchase (Florida) | 831.93 mi (1,338.86 km) |
| West Mifflin to Southern Pines (North Carolina) | 357.95 mi (576.06 km) |
| West Mifflin to Southfield (Michigan) | 227.14 mi (365.55 km) |
| West Mifflin to Southgate (Michigan) | 213.53 mi (343.65 km) |
| West Mifflin to Southlake (Texas) | 1,081.34 mi (1,740.24 km) |
| West Mifflin to Spanaway (Washington) | 2,145.43 mi (3,452.73 km) |
| West Mifflin to Spanish Fork (Utah) | 1,664.83 mi (2,679.29 km) |
| West Mifflin to Spanish Lake (Missouri) | 558.85 mi (899.38 km) |
| West Mifflin to Spanish Springs (Nevada) | 2,086.93 mi (3,358.59 km) |
| West Mifflin to Sparks (Nevada) | 2,090.77 mi (3,364.77 km) |
| West Mifflin to Spartanburg (South Carolina) | 389.98 mi (627.61 km) |
| West Mifflin to Spearfish (South Dakota) | 1,247.51 mi (2,007.67 km) |
| West Mifflin to Speedway (Indiana) | 337.42 mi (543.03 km) |
| West Mifflin to Spencer (Iowa) | 807.89 mi (1,300.17 km) |
| West Mifflin to Spokane (Washington) | 1,911.36 mi (3,076.03 km) |
