| West Des Moines to Steiner Ranch (Texas) | 806.19 mi (1,297.44 km) |
| West Des Moines to Stephenville (Texas) | 689.97 mi (1,110.40 km) |
| West Des Moines to Sterling (Colorado) | 494.10 mi (795.17 km) |
| West Des Moines to Sterling (Illinois) | 211.49 mi (340.36 km) |
| West Des Moines to Sterling (Virginia) | 879.52 mi (1,415.44 km) |
| West Des Moines to Sterling Heights (Michigan) | 555.58 mi (894.12 km) |
| West Des Moines to Steubenville (Ohio) | 689.24 mi (1,109.22 km) |
| West Des Moines to Stevens Point (Wisconsin) | 296.23 mi (476.73 km) |
| West Des Moines to Stevenson Ranch (California) | 1,432.86 mi (2,305.97 km) |
| West Des Moines to Stillwater (Minnesota) | 246.84 mi (397.25 km) |
| West Des Moines to Stillwater (Oklahoma) | 414.25 mi (666.67 km) |
| West Des Moines to Stockbridge (Georgia) | 761.52 mi (1,225.55 km) |
| West Des Moines to Stockton (California) | 1,476.41 mi (2,376.06 km) |
| West Des Moines to Stone Ridge (Virginia) | 873.30 mi (1,405.44 km) |
| West Des Moines to Stonecrest (Georgia) | 756.70 mi (1,217.79 km) |
