| West Des Moines to Spokane Valley (Washington) | 1,222.75 mi (1,967.83 km) |
| West Des Moines to Spout Springs (North Carolina) | 906.92 mi (1,459.55 km) |
| West Des Moines to Spring (Texas) | 798.95 mi (1,285.79 km) |
| West Des Moines to Spring Creek (Nevada) | 1,133.47 mi (1,824.15 km) |
| West Des Moines to Spring Hill (Florida) | 1,102.86 mi (1,774.88 km) |
| West Des Moines to Spring Hill (Tennessee) | 545.93 mi (878.59 km) |
| West Des Moines to Spring Lake (North Carolina) | 911.99 mi (1,467.71 km) |
| West Des Moines to Spring Valley (California) | 1,409.47 mi (2,268.32 km) |
| West Des Moines to Spring Valley (Nevada) | 1,212.55 mi (1,951.40 km) |
| West Des Moines to Spring Valley (New York) | 1,021.93 mi (1,644.63 km) |
| West Des Moines to Springboro (Ohio) | 519.32 mi (835.76 km) |
| West Des Moines to Springdale (Arkansas) | 371.03 mi (597.12 km) |
| West Des Moines to Springdale (New Jersey) | 989.78 mi (1,592.90 km) |
| West Des Moines to Springdale (Ohio) | 513.45 mi (826.31 km) |
| West Des Moines to Springfield (Illinois) | 248.81 mi (400.41 km) |
