| West Des Moines to Somerset (New Jersey) | 1,005.37 mi (1,617.99 km) |
| West Des Moines to Somersworth (New Hampshire) | 1,170.31 mi (1,883.43 km) |
| West Des Moines to Somerton (Arizona) | 1,303.65 mi (2,098.02 km) |
| West Des Moines to Somerville (Massachusetts) | 1,163.00 mi (1,871.66 km) |
| West Des Moines to Somerville (New Jersey) | 999.02 mi (1,607.77 km) |
| West Des Moines to Sonoma (California) | 1,529.14 mi (2,460.91 km) |
| West Des Moines to Soquel (California) | 1,531.89 mi (2,465.34 km) |
| West Des Moines to South Bend (Indiana) | 387.96 mi (624.37 km) |
| West Des Moines to South Bradenton (Florida) | 1,161.47 mi (1,869.21 km) |
| West Des Moines to South Burlington (Vermont) | 1,055.15 mi (1,698.10 km) |
| West Des Moines to South Charleston (West Virginia) | 675.75 mi (1,087.52 km) |
| West Des Moines to South Daytona (Florida) | 1,115.71 mi (1,795.57 km) |
| West Des Moines to South El Monte (California) | 1,416.70 mi (2,279.95 km) |
| West Des Moines to South Elgin (Illinois) | 283.30 mi (455.92 km) |
| West Des Moines to South Euclid (Ohio) | 633.32 mi (1,019.24 km) |
