| West Des Moines to Secaucus (New Jersey) | 1,024.58 mi (1,648.91 km) |
| West Des Moines to Security-Widefield (Colorado) | 608.52 mi (979.32 km) |
| West Des Moines to Sedalia (Missouri) | 198.76 mi (319.87 km) |
| West Des Moines to Sedro-Woolley (Washington) | 1,460.05 mi (2,349.73 km) |
| West Des Moines to Seguin (Texas) | 859.10 mi (1,382.59 km) |
| West Des Moines to Selden (New York) | 1,076.14 mi (1,731.88 km) |
| West Des Moines to Selma (Alabama) | 732.28 mi (1,178.48 km) |
| West Des Moines to Selma (California) | 1,422.19 mi (2,288.79 km) |
| West Des Moines to Selma (Texas) | 864.74 mi (1,391.66 km) |
| West Des Moines to Seminole (Florida) | 1,132.44 mi (1,822.48 km) |
| West Des Moines to Seven Hills (Ohio) | 626.44 mi (1,008.15 km) |
| West Des Moines to Seven Oaks (South Carolina) | 861.52 mi (1,386.47 km) |
| West Des Moines to Severn (Maryland) | 913.49 mi (1,470.12 km) |
| West Des Moines to Severna Park (Maryland) | 920.95 mi (1,482.13 km) |
| West Des Moines to Sevierville (Tennessee) | 674.73 mi (1,085.88 km) |
