| West Des Moines to San Luis (Arizona) | 1,308.39 mi (2,105.65 km) |
| West Des Moines to San Luis Obispo (California) | 1,512.12 mi (2,433.52 km) |
| West Des Moines to San Marcos (California) | 1,404.56 mi (2,260.43 km) |
| West Des Moines to San Marcos (Texas) | 839.62 mi (1,351.24 km) |
| West Des Moines to San Marino (California) | 1,417.55 mi (2,281.32 km) |
| West Des Moines to San Mateo (California) | 1,537.63 mi (2,474.58 km) |
| West Des Moines to San Pablo (California) | 1,530.05 mi (2,462.38 km) |
| West Des Moines to San Rafael (California) | 1,538.73 mi (2,476.35 km) |
| West Des Moines to San Ramon (California) | 1,513.47 mi (2,435.69 km) |
| West Des Moines to San Tan Valley (Arizona) | 1,131.71 mi (1,821.31 km) |
| West Des Moines to Sand Springs (Oklahoma) | 394.97 mi (635.64 km) |
| West Des Moines to Sandusky (Ohio) | 572.93 mi (922.04 km) |
| West Des Moines to Sandy (Oregon) | 1,445.02 mi (2,325.54 km) |
| West Des Moines to Sandy (Utah) | 942.10 mi (1,516.16 km) |
| West Des Moines to Sandy Springs (Georgia) | 734.77 mi (1,182.50 km) |
