| West Des Moines to Owosso (Michigan) | 500.76 mi (805.89 km) |
| West Des Moines to Oxford (Alabama) | 699.21 mi (1,125.27 km) |
| West Des Moines to Oxford (Mississippi) | 547.79 mi (881.58 km) |
| West Des Moines to Oxford (Ohio) | 494.87 mi (796.41 km) |
| West Des Moines to Oxnard (California) | 1,469.05 mi (2,364.20 km) |
| West Des Moines to Oxon Hill (Maryland) | 906.14 mi (1,458.30 km) |
| West Des Moines to Ozark (Alabama) | 830.45 mi (1,336.48 km) |
| West Des Moines to Ozark (Missouri) | 313.45 mi (504.46 km) |
| West Des Moines to Pace (Florida) | 840.18 mi (1,352.15 km) |
| West Des Moines to Pacific Grove (California) | 1,540.13 mi (2,478.60 km) |
| West Des Moines to Pacifica (California) | 1,544.87 mi (2,486.23 km) |
| West Des Moines to Paducah (Kentucky) | 413.67 mi (665.74 km) |
| West Des Moines to Pahrump (Nevada) | 1,246.21 mi (2,005.58 km) |
| West Des Moines to Painesville (Ohio) | 646.40 mi (1,040.28 km) |
| West Des Moines to Palatine (Illinois) | 297.89 mi (479.40 km) |
