| West Des Moines to Odenton (Maryland) | 914.91 mi (1,472.41 km) |
| West Des Moines to Odessa (Texas) | 818.54 mi (1,317.31 km) |
| West Des Moines to Ogden (Utah) | 941.29 mi (1,514.86 km) |
| West Des Moines to Oildale (California) | 1,423.61 mi (2,291.08 km) |
| West Des Moines to Ojus (Florida) | 1,327.98 mi (2,137.19 km) |
| West Des Moines to Okemos (Michigan) | 486.30 mi (782.62 km) |
| West Des Moines to Oklahoma City (Oklahoma) | 466.21 mi (750.29 km) |
| West Des Moines to Okmulgee (Oklahoma) | 427.53 mi (688.05 km) |
| West Des Moines to Olathe (Kansas) | 192.37 mi (309.59 km) |
| West Des Moines to Old Jamestown (Missouri) | 262.96 mi (423.19 km) |
| West Des Moines to Oldsmar (Florida) | 1,123.69 mi (1,808.40 km) |
| West Des Moines to Olean (New York) | 790.14 mi (1,271.60 km) |
| West Des Moines to Olive Branch (Mississippi) | 502.78 mi (809.15 km) |
| West Des Moines to Olivehurst (California) | 1,466.87 mi (2,360.70 km) |
| West Des Moines to Olney (Maryland) | 893.92 mi (1,438.62 km) |
