| West Des Moines to Des Plaines (Illinois) | 304.65 mi (490.29 km) |
| West Des Moines to Desert Hot Springs (California) | 1,344.52 mi (2,163.79 km) |
| West Des Moines to DeSoto (Texas) | 641.38 mi (1,032.20 km) |
| West Des Moines to Destin (Florida) | 871.73 mi (1,402.91 km) |
| West Des Moines to Destrehan (Louisiana) | 823.11 mi (1,324.67 km) |
| West Des Moines to Detroit (Michigan) | 551.19 mi (887.06 km) |
| West Des Moines to Diamond Bar (California) | 1,406.69 mi (2,263.85 km) |
| West Des Moines to Diamond Springs (California) | 1,437.20 mi (2,312.96 km) |
| West Des Moines to Dickinson (North Dakota) | 578.34 mi (930.75 km) |
| West Des Moines to Dickinson (Texas) | 838.90 mi (1,350.08 km) |
| West Des Moines to Dickson (Tennessee) | 512.59 mi (824.93 km) |
| West Des Moines to Difficult Run (Virginia) | 884.58 mi (1,423.59 km) |
| West Des Moines to Dinuba (California) | 1,411.77 mi (2,272.02 km) |
| West Des Moines to Discovery Bay (California) | 1,492.84 mi (2,402.49 km) |
| West Des Moines to Dix Hills (New York) | 1,061.91 mi (1,708.98 km) |
