| West Des Moines to Sestu | 5,049.07 mi (8,125.69 km) |
| West Des Moines to Settimo Torinese | 4,741.68 mi (7,631.00 km) |
| West Des Moines to Seveso | 4,771.97 mi (7,679.74 km) |
| West Des Moines to Sezze | 5,106.98 mi (8,218.89 km) |
| West Des Moines to Siano | 5,202.04 mi (8,371.88 km) |
| West Des Moines to Siena | 4,957.66 mi (7,978.58 km) |
| West Des Moines to Signa | 4,928.03 mi (7,930.89 km) |
| West Des Moines to Silea | 4,889.18 mi (7,868.37 km) |
| West Des Moines to Silvi Paese | 5,098.54 mi (8,205.30 km) |
| West Des Moines to Sinalunga | 4,977.58 mi (8,010.65 km) |
| West Des Moines to Siniscola | 5,016.51 mi (8,073.29 km) |
| West Des Moines to Sinnai | 5,053.46 mi (8,132.76 km) |
| West Des Moines to Siracusa | 5,402.07 mi (8,693.79 km) |
| West Des Moines to Solaro | 4,771.17 mi (7,678.46 km) |
| West Des Moines to Soliera | 4,878.93 mi (7,851.87 km) |
