| Weslaco to Shelbyville (Tennessee) | 939.27 mi (1,511.61 km) |
| Weslaco to Shelton (Connecticut) | 1,759.56 mi (2,831.73 km) |
| Weslaco to Shelton (Washington) | 1,996.22 mi (3,212.61 km) |
| Weslaco to Shenandoah (Louisiana) | 516.11 mi (830.60 km) |
| Weslaco to Shepherdsville (Kentucky) | 1,086.32 mi (1,748.26 km) |
| Weslaco to Sheridan (Wyoming) | 1,381.02 mi (2,222.53 km) |
| Weslaco to Sherman (Texas) | 522.37 mi (840.68 km) |
| Weslaco to Sherrelwood (Colorado) | 1,027.92 mi (1,654.27 km) |
| Weslaco to Sherwood (Arkansas) | 691.86 mi (1,113.44 km) |
| Weslaco to Sherwood (Oregon) | 1,909.04 mi (3,072.30 km) |
| Weslaco to Shiloh (Illinois) | 976.31 mi (1,571.22 km) |
| Weslaco to Shiloh (Ohio) | 1,232.10 mi (1,982.88 km) |
| Weslaco to Shiloh (Pennsylvania) | 1,547.68 mi (2,490.75 km) |
| Weslaco to Shirley (New York) | 1,755.04 mi (2,824.46 km) |
| Weslaco to Shively (Kentucky) | 1,092.67 mi (1,758.48 km) |
