| Weslaco to Seymour (Indiana) | 1,127.75 mi (1,814.93 km) |
| Weslaco to Seymour (Tennessee) | 1,074.90 mi (1,729.88 km) |
| Weslaco to Shady Hills (Florida) | 960.08 mi (1,545.09 km) |
| Weslaco to Shafter (California) | 1,409.61 mi (2,268.55 km) |
| Weslaco to Shaker Heights (Ohio) | 1,412.67 mi (2,273.48 km) |
| Weslaco to Shakopee (Minnesota) | 1,310.40 mi (2,108.88 km) |
| Weslaco to Sharon (Pennsylvania) | 1,441.96 mi (2,320.61 km) |
| Weslaco to Sharonville (Ohio) | 1,199.29 mi (1,930.07 km) |
| Weslaco to Shasta Lake (California) | 1,717.85 mi (2,764.61 km) |
| Weslaco to Shawnee (Kansas) | 907.17 mi (1,459.94 km) |
| Weslaco to Shawnee (Oklahoma) | 638.07 mi (1,026.88 km) |
| Weslaco to Sheboygan (Wisconsin) | 1,343.86 mi (2,162.74 km) |
| Weslaco to Shelby (North Carolina) | 1,160.10 mi (1,867.01 km) |
| Weslaco to Shelbyville (Indiana) | 1,162.12 mi (1,870.25 km) |
| Weslaco to Shelbyville (Kentucky) | 1,115.48 mi (1,795.19 km) |
