| Weslaco to Olympia (Washington) | 1,980.69 mi (3,187.62 km) |
| Weslaco to Olympia Heights (Florida) | 1,096.12 mi (1,764.04 km) |
| Weslaco to Omaha (Nebraska) | 1,049.33 mi (1,688.73 km) |
| Weslaco to On Top of the World Designated Place (Florida) | 981.59 mi (1,579.72 km) |
| Weslaco to Onalaska (Wisconsin) | 1,282.42 mi (2,063.86 km) |
| Weslaco to Oneida (New York) | 1,715.35 mi (2,760.59 km) |
| Weslaco to Oneonta (New York) | 1,715.75 mi (2,761.23 km) |
| Weslaco to Ontario (California) | 1,289.93 mi (2,075.94 km) |
| Weslaco to Ontario (Oregon) | 1,627.67 mi (2,619.49 km) |
| Weslaco to Opa-locka (Florida) | 1,100.22 mi (1,770.63 km) |
| Weslaco to Opelika (Alabama) | 880.98 mi (1,417.80 km) |
| Weslaco to Opelousas (Louisiana) | 468.85 mi (754.54 km) |
| Weslaco to Orange (California) | 1,296.23 mi (2,086.09 km) |
| Weslaco to Orange (Texas) | 375.81 mi (604.80 km) |
| Weslaco to Orange City (Florida) | 1,039.89 mi (1,673.53 km) |
