| Weslaco to Odenton (Maryland) | 1,520.30 mi (2,446.69 km) |
| Weslaco to Odessa (Texas) | 474.75 mi (764.04 km) |
| Weslaco to Ogden (Utah) | 1,311.52 mi (2,110.69 km) |
| Weslaco to Oildale (California) | 1,399.40 mi (2,252.12 km) |
| Weslaco to Ojus (Florida) | 1,105.75 mi (1,779.53 km) |
| Weslaco to Okemos (Michigan) | 1,376.35 mi (2,215.02 km) |
| Weslaco to Oklahoma City (Oklahoma) | 643.71 mi (1,035.95 km) |
| Weslaco to Okmulgee (Oklahoma) | 663.60 mi (1,067.96 km) |
| Weslaco to Olathe (Kansas) | 898.09 mi (1,445.33 km) |
| Weslaco to Old Jamestown (Missouri) | 983.40 mi (1,582.62 km) |
| Weslaco to Oldsmar (Florida) | 950.48 mi (1,529.65 km) |
| Weslaco to Olean (New York) | 1,561.51 mi (2,513.01 km) |
| Weslaco to Olive Branch (Mississippi) | 776.74 mi (1,250.04 km) |
| Weslaco to Olivehurst (California) | 1,628.64 mi (2,621.04 km) |
| Weslaco to Olney (Maryland) | 1,505.52 mi (2,422.90 km) |
