| Weslaco to Indianapolis (Indiana) | 1,162.27 mi (1,870.50 km) |
| Weslaco to Indianola (Iowa) | 1,080.29 mi (1,738.56 km) |
| Weslaco to Indio (California) | 1,208.83 mi (1,945.42 km) |
| Weslaco to Inglewood (California) | 1,328.01 mi (2,137.23 km) |
| Weslaco to Inkster (Michigan) | 1,390.28 mi (2,237.43 km) |
| Weslaco to Inver Grove Heights (Minnesota) | 1,318.41 mi (2,121.78 km) |
| Weslaco to Inwood (New York) | 1,708.93 mi (2,750.26 km) |
| Weslaco to Iona (Florida) | 992.11 mi (1,596.64 km) |
| Weslaco to Ionia (Michigan) | 1,371.10 mi (2,206.57 km) |
| Weslaco to Iowa City (Iowa) | 1,132.00 mi (1,821.78 km) |
| Weslaco to Irmo (South Carolina) | 1,141.47 mi (1,837.02 km) |
| Weslaco to Irondale (Alabama) | 848.17 mi (1,365.00 km) |
| Weslaco to Ironton (Ohio) | 1,233.36 mi (1,984.90 km) |
| Weslaco to Irvine (California) | 1,290.83 mi (2,077.39 km) |
| Weslaco to Irving (Texas) | 466.83 mi (751.29 km) |
