| Weslaco to Elyria (Ohio) | 1,387.17 mi (2,232.43 km) |
| Weslaco to Emeryville (California) | 1,629.54 mi (2,622.50 km) |
| Weslaco to Emmaus (Pennsylvania) | 1,626.17 mi (2,617.07 km) |
| Weslaco to Emporia (Kansas) | 852.32 mi (1,371.67 km) |
| Weslaco to Encinitas (California) | 1,249.33 mi (2,010.60 km) |
| Weslaco to Endicott (New York) | 1,659.70 mi (2,671.03 km) |
| Weslaco to Endwell (New York) | 1,662.28 mi (2,675.17 km) |
| Weslaco to Englewood (Colorado) | 1,015.76 mi (1,634.70 km) |
| Weslaco to Englewood (Florida) | 967.25 mi (1,556.64 km) |
| Weslaco to Englewood (New Jersey) | 1,707.65 mi (2,748.19 km) |
| Weslaco to Englewood (Ohio) | 1,231.73 mi (1,982.28 km) |
| Weslaco to Enid (Oklahoma) | 707.99 mi (1,139.40 km) |
| Weslaco to Ennis (Texas) | 433.72 mi (698.00 km) |
| Weslaco to Ensley (Florida) | 717.53 mi (1,154.75 km) |
| Weslaco to Enterprise (Alabama) | 816.89 mi (1,314.65 km) |
