| Wade Hampton to Enterprise (Nevada) | 1,844.39 mi (2,968.25 km) |
| Wade Hampton to Enumclaw (Washington) | 2,205.96 mi (3,550.15 km) |
| Wade Hampton to Ephrata (Pennsylvania) | 497.41 mi (800.51 km) |
| Wade Hampton to Erie (Colorado) | 1,291.25 mi (2,078.07 km) |
| Wade Hampton to Erie (Pennsylvania) | 514.53 mi (828.06 km) |
| Wade Hampton to Erlanger (Kentucky) | 311.19 mi (500.80 km) |
| Wade Hampton to Escanaba (Michigan) | 791.07 mi (1,273.10 km) |
| Wade Hampton to Escondido (California) | 1,983.40 mi (3,191.97 km) |
| Wade Hampton to Española (New Mexico) | 1,334.99 mi (2,148.45 km) |
| Wade Hampton to Essex (Maryland) | 445.44 mi (716.87 km) |
| Wade Hampton to Essex Junction (Vermont) | 824.06 mi (1,326.19 km) |
| Wade Hampton to Estelle (Louisiana) | 571.23 mi (919.31 km) |
| Wade Hampton to Estero (Florida) | 585.02 mi (941.50 km) |
| Wade Hampton to Euclid (Ohio) | 465.59 mi (749.29 km) |
| Wade Hampton to Eufaula (Alabama) | 261.83 mi (421.37 km) |
