| Villanueva de la Serena to Roznava | 1,463.47 mi (2,355.23 km) |
| Villanueva de la Serena to Ruzomberok | 1,420.13 mi (2,285.48 km) |
| Villanueva de la Serena to Sabinov | 1,496.84 mi (2,408.93 km) |
| Villanueva de la Serena to Sal'a | 1,336.93 mi (2,151.57 km) |
| Villanueva de la Serena to Samorin | 1,309.46 mi (2,107.38 km) |
| Villanueva de la Serena to Senec | 1,317.86 mi (2,120.89 km) |
| Villanueva de la Serena to Senica | 1,327.90 mi (2,137.05 km) |
| Villanueva de la Serena to Sered' | 1,333.84 mi (2,146.61 km) |
| Villanueva de la Serena to Skalica | 1,326.17 mi (2,134.27 km) |
| Villanueva de la Serena to Smizany | 1,469.66 mi (2,365.18 km) |
| Villanueva de la Serena to Snina | 1,540.86 mi (2,479.78 km) |
| Villanueva de la Serena to Spisska Nova Ves | 1,471.06 mi (2,367.44 km) |
| Villanueva de la Serena to Stara L'ubovna | 1,483.80 mi (2,387.95 km) |
| Villanueva de la Serena to Stara Tura | 1,344.30 mi (2,163.45 km) |
| Villanueva de la Serena to Stropkov | 1,523.28 mi (2,451.48 km) |
