| Villanueva de la Serena to Ede | 1,058.01 mi (1,702.71 km) |
| Villanueva de la Serena to Eemnes | 1,059.17 mi (1,704.58 km) |
| Villanueva de la Serena to Eerbeek | 1,071.06 mi (1,723.70 km) |
| Villanueva de la Serena to Eersel | 1,010.11 mi (1,625.62 km) |
| Villanueva de la Serena to Eijsden | 989.19 mi (1,591.95 km) |
| Villanueva de la Serena to Eindhoven | 1,019.01 mi (1,639.94 km) |
| Villanueva de la Serena to Elburg | 1,084.99 mi (1,746.13 km) |
| Villanueva de la Serena to Emmeloord | 1,097.29 mi (1,765.91 km) |
| Villanueva de la Serena to Emmen | 1,129.68 mi (1,818.04 km) |
| Villanueva de la Serena to Enkhuizen | 1,086.15 mi (1,747.99 km) |
| Villanueva de la Serena to Enschede | 1,098.82 mi (1,768.38 km) |
| Villanueva de la Serena to Epe | 1,082.67 mi (1,742.38 km) |
| Villanueva de la Serena to Ermelo | 1,070.85 mi (1,723.36 km) |
| Villanueva de la Serena to Etten-Leur | 1,005.35 mi (1,617.96 km) |
| Villanueva de la Serena to Franeker | 1,120.35 mi (1,803.02 km) |
