| Villanueva de la Serena to Santa Venerina | 1,135.62 mi (1,827.61 km) |
| Villanueva de la Serena to Santeramo in Colle | 1,199.80 mi (1,930.89 km) |
| Villanueva de la Serena to Santo Stefano di Magra | 886.31 mi (1,426.37 km) |
| Villanueva de la Serena to Santo Stino di Livenza | 1,049.87 mi (1,689.60 km) |
| Villanueva de la Serena to Sarezzo | 936.48 mi (1,507.12 km) |
| Villanueva de la Serena to Sarno | 1,087.36 mi (1,749.94 km) |
| Villanueva de la Serena to Saronno | 884.83 mi (1,424.00 km) |
| Villanueva de la Serena to Sarzana | 887.36 mi (1,428.07 km) |
| Villanueva de la Serena to Sassari | 770.46 mi (1,239.93 km) |
| Villanueva de la Serena to Sasso Marconi | 954.19 mi (1,535.62 km) |
| Villanueva de la Serena to Sassuolo | 935.63 mi (1,505.75 km) |
| Villanueva de la Serena to Sava | 1,242.79 mi (2,000.08 km) |
| Villanueva de la Serena to Saviano | 1,082.17 mi (1,741.58 km) |
| Villanueva de la Serena to Savigliano | 794.04 mi (1,277.89 km) |
| Villanueva de la Serena to Savignano sul Panaro | 945.74 mi (1,522.02 km) |
