| Villanueva de la Serena to Senftenberg | 1,289.02 mi (2,074.48 km) |
| Villanueva de la Serena to Siegburg | 1,033.11 mi (1,662.63 km) |
| Villanueva de la Serena to Siegen | 1,061.65 mi (1,708.56 km) |
| Villanueva de la Serena to Sigmaringen | 978.26 mi (1,574.36 km) |
| Villanueva de la Serena to Simbach am Inn | 1,134.80 mi (1,826.28 km) |
| Villanueva de la Serena to Simmerath | 996.35 mi (1,603.48 km) |
| Villanueva de la Serena to Sindelfingen | 995.64 mi (1,602.33 km) |
| Villanueva de la Serena to Sinsheim | 1,014.20 mi (1,632.20 km) |
| Villanueva de la Serena to Sinzheim | 967.74 mi (1,557.42 km) |
| Villanueva de la Serena to Sinzig | 1,021.61 mi (1,644.12 km) |
| Villanueva de la Serena to Soest | 1,098.75 mi (1,768.26 km) |
| Villanueva de la Serena to Solingen | 1,048.31 mi (1,687.10 km) |
| Villanueva de la Serena to Soltau | 1,219.73 mi (1,962.96 km) |
| Villanueva de la Serena to Sommerda | 1,174.18 mi (1,889.66 km) |
| Villanueva de la Serena to Sondershausen | 1,174.93 mi (1,890.87 km) |
